|
Mutation Information
|
Mutation Site
|
S69C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Viral Reference
|
U95551
|
Literature Information
|
PubMed PMID
|
23261845
|
|
Published Year
|
2013 |
|
Journal
|
Antiviral research |
|
Title
|
The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir. |
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Author
|
Qin B,Budeus B,Cao L,Wu C,Wang Y,Zhang X,Rayner S,Hoffmann D,Lu M,Chen X |
|
Evidence
|
The mutations at rtL77F (sS69C), rtF88L (sF80Y), and rtP177G (sR169G) also significantly affected HBsAg expression.
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HBV Mutation Detail Information