Mutation Information
Mutation Site
|
S653Q |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Pol |
Immune Escape
|
Y |
Country
|
Vietnam |
Literature Information
PubMed PMID
|
33031103
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2021 |
Journal
|
AIDS (London, England) |
Title
|
Critical effect of Pol escape mutations associated with detrimental allele HLA-C*15: 05 on clinical outcome in HIV-1 subtype A/E infection. |
Author
|
Murakoshi H,Chikata T,Akahoshi T,Zou C,Borghan MA,Van Tran G,Nguyen TV,Van Nguyen K,Kuse N,Takiguchi M |
Evidence
|
We detected Pol S653K/S653Q mutations in 17 of 23 HLA-C∗15:05+ individuals infected with mutants at Pol653 other than Pol S653A/T/L (Fig. (Fig.3a).3a).
|
|
|