HPV Mutation Detail Information

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Mutation Information
Mutation Site S63F
Mutation Type Amino acid level
Gene/Protein/Region Type E7
Amino acid_Mutation C749T
Genotype/Subtype HPV16
Viral Reference HQ644251.1
Country China
Literature Information
PubMed PMID 30981880
Disease Cervical carcinoma
Published Year 2019
Journal Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Title Human papillomavirus type 16 E6 and E7 gene variations associated with cervical cancer in a Han Chinese population.
Author Zhou Z,Yang H,Yang L,Yao Y,Dai S,Shi L,Li C,Yang L,Yan Z,Yao Y
Evidence When the distribution of the HPV16 E6 and E7 gene variations was compared, the distribution of only A131C (R10R) in the E6 gene showed a different trend between the case and control groups and C749T (S63F) in the E7 gene was significantly different between the case and control groups (P = 0.071 and P = 4.861 x 10-10, respectively).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation