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Mutation Information
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Mutation Site
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S598A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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BRLF1 |
Literature Information
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PubMed PMID
|
19232420
|
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Published Year
|
2009 |
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Journal
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Virology |
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Title
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Two phenylalanines in the C-terminus of Epstein-Barr virus Rta protein reciprocally modulate its DNA binding and transactivation function. |
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Author
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Chen LW,Raghavan V,Chang PJ,Shedd D,Heston L,Delecluse HJ,Miller G |
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Evidence
|
However, the S598A mutant protein behaved like wild-type Rta; the interaction between S598A and a duplex oligonucleotide containing the RRE from the BMLF1 promoter was very weak (Fig. 2B, lane 4).
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EBV Mutation Detail Information