HPV Mutation Detail Information

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Mutation Information
Mutation Site S49N
Mutation Type Amino acid level
Gene/Protein/Region Type L1
Genotype/Subtype HPV45
Viral Reference X74479.1
Country Indonesia
Literature Information
PubMed PMID 32986347
Disease Cervical carcinoma
Published Year 2020
Journal Asian Pacific journal of cancer prevention : APJCP
Title Phylogeny and In Silico Structure Analysis of Major Capsid Protein (L1) Human Papillomavirus 45 from Indonesian Isolates.
Author Pradini GW,Sahiratmadja E,Suhandono S,Sudigdoadi S,Yusuf M,Firdaus ARR,Susanto H
Evidence Mutations of S49N, N81S, N379T, S383N and Q392H might not affect the antibody binding, since the structural properties between asparagine (N), threonine (T), serine (S), and glutamine (Q) are similarly polar.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation