Mutation Information
Mutation Site
|
S412D |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
EBNA2 |
Literature Information
PubMed PMID
|
31283782
|
Published Year
|
2019 |
Journal
|
PLoS pathogens |
Title
|
Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity. |
Author
|
Ponnusamy R,Khatri R,Correia PB,Wood CD,Mancini EJ,Farrell PJ,West MJ |
Evidence
|
Replacing the serine that occurs at the equivalent position in type 2 EBNA2 (amino acid 409 of type 2 EBNA2) with aspartate (mutant S442D) confers efficient growth maintenance function.
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