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Mutation Information
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Mutation Site
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S383A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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EBNA1 |
Literature Information
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PubMed PMID
|
27009860
|
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Published Year
|
2016 |
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Journal
|
Oncotarget |
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Title
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ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivation. |
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Author
|
Noh KW,Park J,Joo EH,Lee EK,Choi EY,Kang MS |
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Evidence
|
In accordance, ERK2 was found to phosphorylate EBNA1 serine 383 in a reaction suppressed by H20 (a structural congener of the ERK inhibitor), U0126 (an inhibitor of MEK kinase), and mutations at substrate (S383A) or putative ERK docking sites.
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EBV Mutation Detail Information