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Mutation Information
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Mutation Site
|
S37N |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
PR |
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Genotype/Subtype
|
B |
Literature Information
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PubMed PMID
|
32411655
|
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Published Year
|
2020 |
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Journal
|
Frontiers in chemistry |
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Title
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An Innovative Sequence-to-Structure-Based Approach to Drug Resistance Interpretation and Prediction: The Use of Molecular Interaction Fields to Detect HIV-1 Protease Binding-Site Dissimilarities. |
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Author
|
Alves NG,Mata AI,Luís JP,Brito RMM,Simões CJV |
|
Evidence
|
The structure of 1NH0 holds 99% sequence identity (98/99) with the consensus B amino acid sequence of protease, HXB2 (henceforth referred to as consensus sequence), with one single mutation at position 37 (S37N), has 100% coverage of the sequence, and has been determined at 1.03 Å X-ray resolution.
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HIV Mutation Detail Information