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Mutation Information
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Mutation Site
|
S318A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tax |
Literature Information
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PubMed PMID
|
10567539
|
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Published Year
|
1999 |
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Journal
|
Molecular and cellular biology |
|
Title
|
PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner. |
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Author
|
Jiang H,Lu H,Schiltz RL,Pise-Masison CA,Ogryzko VV,Nakatani Y,Brady JN |
|
Evidence
|
Point mutations at Tax amino acid 318 (Tax S318A) or 319 to 320 (Tax M47), which have decreased or no activity on the HTLV-1 promoter, are defective for PCAF binding.
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HTLV1 Mutation Detail Information