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Mutation Information
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Mutation Site
|
S298N |
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Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gp120 |
Literature Information
|
PubMed PMID
|
17686153
|
|
Published Year
|
2007 |
|
Journal
|
Retrovirology |
|
Title
|
The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment. |
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Author
|
Melikyan GB,Platt EJ,Kabat D |
|
Evidence
|
Note that the S298N substitution is one of the three adaptive mutations in JRCSF Env permitting the usage of CCR5(Y14N) and CCR5(Delta18) for entry.
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HIV Mutation Detail Information