|
Mutation Information
|
Mutation Site
|
S278C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gag |
|
Viral Reference
|
K03455.1
|
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
30201008
|
|
Clinical information
|
Yes
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Retrovirology |
|
Title
|
Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control. |
|
Author
|
Caetano DG,Côrtes FH,Bello G,Teixeira SLM,Hoagland B,Grinsztejn B,Veloso VG,Guimarães ML,Morgado MG |
|
Evidence
|
For those individuals with none (EC02, EC52) or very few (EC17) viral blips during clinical follow-up, the majority of the epitope mutations detected were rare (< 2%) in both Gag and Nef, except for Gag epitope positions A83S (adjacent to EV9) and S278C (RI9), which each corresponded roughly to 23% in EC02 VL.
|
|
|
HIV Mutation Detail Information