|
Mutation Information
|
Mutation Site
|
S21T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
C |
|
Genotype/Subtype
|
D |
|
Viral Reference
|
X72702.1;
X02496.1;
Z35716;
M32138.1;
DQ315780.1;
AY945307.1;
X01587.1;
AB033556.1;
D50519.1;
D23680.1;
M38636.1;
AY233290.1;
M57663.2;
AF297621.1;
AY934772.1;
AY233274.1 |
|
Immune Escape
|
Y |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
26201521
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
Hepatology international |
|
Title
|
Naturally occurring core immune-escape and carboxy-terminal mutations\truncations in patients with e antigen negative chronic hepatitis B. |
|
Author
|
Chauhan R,Sarin SK,Kumar M,Bhattacharjee J |
|
Evidence
|
When frequency of core immune escape mutations was compared among CHB and decompensated patients, and cT12S: (27 vs. 10%, p < 0.05), cS21T (16 vs. 1.35%, p < 0.01), cT67P/N: (20 vs. 4%, p < 0.001), cE113D (11.37 vs. 1.35%, p < 0.05), and cP130T/Q (7 vs. 0%, p < 0.001) mutations were found to be significantly higher in decompensated patients.
|
|
|
HBV Mutation Detail Information