HBV Mutation Detail Information

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Mutation Information

Mutation Site	S21Q
Mutation Type	Amino acid level
Gene/Protein/Region Type	C
Amino acid_Mutation	T1961C
Country	Japan

Literature Information

PubMed PMID	33959934
Disease	Chronic hepatitis B
Published Year	2021
Journal	Clinical journal of gastroenterology
Title	Spontaneous reactivation of hepatitis B virus with a frameshift mutation in the precore region in an elderly hepatitis B virus carrier with lifestyle-related diseases.
Author	Takakusagi S,Takagi H,Yokoyama Y,Kizawa K,Marubashi K,Kosone T,Nagashima S,Takahashi M,Murata K,Okamoto H
Evidence	Her HBV genome was typed as subgenotype B1 and possessed a frameshift mutation due to an insertion of T after nucleotide (nt) 1817 and G to A mutations at nt 1896 and nt 1899 (G1896A/G1899A) in the precore region as well as serine to glutamine substitution of amino acid 21 in the core protein

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation