HBV Mutation Detail Information

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Mutation Information

Mutation Site	S212F
Mutation Type	Amino acid level
Gene/Protein/Region Type	S

Literature Information

PubMed PMID	22967103
Published Year	2012
Journal	Journal of viral hepatitis
Title	Mutations associated with occult hepatitis B virus infection result in decreased surface antigen expression in vitro.
Author	Martin CM,Welge JA,Rouster SD,Shata MT,Sherman KE,Blackard JT
Evidence	However, overall HBsAg levels were higher in the supernatant, while lysate HBsAg levels were lower, indicating increased HBsAg secretion with the second C-HBV backbone, presumably due to the 2 amino acid mutations (G164E and S212F) that differentiate the C-HBV sequences.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation