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EBV Mutation Detail Information

> S208E Search Result


Mutation Information
Mutation Site S208E
Mutation Type Amino acid level
Gene/Protein/Region Type BZLF1
Literature Information
PubMed PMID 19144704
Published Year 2009
Journal Journal of virology
Title Interaction of Epstein-Barr virus BZLF1 C-terminal tail structure and core zipper is required for DNA replication but not for promoter transactivation.
Author McDonald CM,Petosa C,Farrell PJ
Evidence The restoration of BZLF1 DNA replication activity by the complementation of two deleterious mutations (S208E and D236K) indicates that the interaction of the C-terminal tail and the core zipper is required for DNA replication, identifying a functional role for this structural feature unique to BZLF1.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation