EBV Mutation Detail Information

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Mutation Information
Mutation Site S186T
Mutation Type Amino acid level
Gene/Protein/Region Type BZLF1
Literature Information
PubMed PMID 15919888
Published Year 2005
Journal Journal of virology
Title BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186.
Author Bhende PM,Seaman WT,Delecluse HJ,Kenney SC
Evidence A Z mutant containing threonine at residue 186 [Z(S186T)] bound only to the methylated form of the ZRE-2 site in Rp and induced lytic EBV gene transcription from the methylated, but not demethylated, form of the viral genome.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation