Mutation Information
Mutation Site
|
S186T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
BZLF1 |
Literature Information
PubMed PMID
|
15919888
|
Published Year
|
2005 |
Journal
|
Journal of virology |
Title
|
BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186. |
Author
|
Bhende PM,Seaman WT,Delecluse HJ,Kenney SC |
Evidence
|
A Z mutant containing threonine at residue 186 [Z(S186T)] bound only to the methylated form of the ZRE-2 site in Rp and induced lytic EBV gene transcription from the methylated, but not demethylated, form of the viral genome.
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