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Mutation Information
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Mutation Site
|
S186D |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
BZLF1 |
Literature Information
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PubMed PMID
|
15919888
|
|
Published Year
|
2005 |
|
Journal
|
Journal of virology |
|
Title
|
BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186. |
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Author
|
Bhende PM,Seaman WT,Delecluse HJ,Kenney SC |
|
Evidence
|
Finally, a Z mutant containing an aspartic acid at position 186 [Z(S186D)] did not bind to either the consensus AP-1 site or to the methylated or unmethylated Rp ZRE-2 site and did not induce lytic gene transcription.
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EBV Mutation Detail Information