EBV Mutation Detail Information

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Mutation Information

Mutation Site	S186A
Mutation Type	Amino acid level
Gene/Protein/Region Type	BZLF1
Viral Reference	V01555.2

Literature Information

PubMed PMID	9060666
Published Year	1997
Journal	Journal of virology
Title	Alteration of a single serine in the basic domain of the Epstein-Barr virus ZEBRA protein separates its functions of transcriptional activation and disruption of latency.
Author	Francis AL,Gradoville L,Miller G
Evidence	We generated a point mutant of ZEBRA, Z(S186A), that was not impaired in its ability to activate transcription; however, this mutation abolished its ability to initiate the viral lytic cascade.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation