|
Mutation Information
|
Mutation Site
|
S186A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
BZLF1 |
Literature Information
|
PubMed PMID
|
19232420
|
|
Published Year
|
2009 |
|
Journal
|
Virology |
|
Title
|
Two phenylalanines in the C-terminus of Epstein-Barr virus Rta protein reciprocally modulate its DNA binding and transactivation function. |
|
Author
|
Chen LW,Raghavan V,Chang PJ,Shedd D,Heston L,Delecluse HJ,Miller G |
|
Evidence
|
The ZEBRA mutant Z(S186A) does not by itself activate BMRF1, but can synergize with Rta to activate expression of this gene, both the transcript and the protein.
|
|
|
EBV Mutation Detail Information