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EBV Mutation Detail Information

> S186A Search Result


Mutation Information
Mutation Site S186A
Mutation Type Amino acid level
Gene/Protein/Region Type BZLF1
Literature Information
PubMed PMID 18937960
Published Year 2008
Journal Virology
Title Mutations of amino acids in the DNA-recognition domain of Epstein-Barr virus ZEBRA protein alter its sub-nuclear localization and affect formation of replication compartments.
Author Park R,Heston L,Shedd D,Delecluse HJ,Miller G
Evidence The distribution of S186A mutant ZEBRA protein, defective for activation of Rta and EA-D, was identical to WT, except that the mutant ZEBRA was never found in globular compartments. Co-expression of Rta with S186A mutant rescued diffuse EA-D but not globular replication compartments.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation