EBV Mutation Detail Information

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Mutation Information

Mutation Site	S186A
Mutation Type	Amino acid level
Gene/Protein/Region Type	BZLF1

Literature Information

PubMed PMID	16406456
Published Year	2006
Journal	Virology
Title	Regulation of the expression of the Epstein-Barr virus early gene BFRF1.
Author	Granato M,Farina A,Gonnella R,Santarelli R,Frati L,Faggioni A,Angeloni A
Evidence	However, a co-operative effect between ZEBRA and RTA in the expression of BFRF1 is evident since the transfection of RTA can rescue the transactivating capacity of a mutant of the ZEBRA protein, known as Z(S186A), that has a substitution affecting the DNA binding region.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation