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Mutation Information
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Mutation Site
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S173F |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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BZLF1 |
Literature Information
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PubMed PMID
|
23077295
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Published Year
|
2013 |
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Journal
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Journal of virology |
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Title
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Essential role of Rta in lytic DNA replication of Epstein-Barr virus. |
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Author
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El-Guindy A,Ghiassi-Nejad M,Golden S,Delecluse HJ,Miller G |
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Evidence
|
Expression of Rta or RPs together with Z(S173F) did not restore genome amplification or late gene expression (Fig. 4, lanes 4 and 5). These results show that Rta and replication proteins each can suppress the replication defect in the mutant Z(S173A) but not Z(S173F).
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EBV Mutation Detail Information