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Mutation Information
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Mutation Site
|
S173A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
BZLF1 |
Literature Information
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PubMed PMID
|
17215287
|
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Published Year
|
2007 |
|
Journal
|
Journal of virology |
|
Title
|
Phosphoacceptor site S173 in the regulatory domain of Epstein-Barr Virus ZEBRA protein is required for lytic DNA replication but not for activation of viral early genes. |
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Author
|
El-Guindy A,Heston L,Delecluse HJ,Miller G |
|
Evidence
|
An independent assay based on ZEBRA solubility demonstrated a marked defect in DNA binding by the Z(S173A) mutant.
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EBV Mutation Detail Information