Mutation Information
Mutation Site
|
S16A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Tat |
Literature Information
PubMed PMID
|
17083724
|
Published Year
|
2006 |
Journal
|
Retrovirology |
Title
|
Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription. |
Author
|
Ammosova T,Berro R,Jerebtsova M,Jackson A,Charles S,Klase Z,Southerland W,Gordeuk VR,Kashanchi F,Nekhai S |
Evidence
|
While we could detect phosphorylation of WT Tat (Fig. 8C, lane 2), the Tat S16A mutant and Tat S46A mutant were about 2-3 fold less phosphorylated (Fig. 8C, middle and lower panels, lanes 3 and 4).
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