HIV Mutation Detail Information

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Mutation Information

Mutation Site	S162R
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	B
Immune Escape	Y
Country	Europe;Italy;Asia; Africa;North America;South America

Literature Information

PubMed PMID	30356083
Disease	HIV infection/AIDS
Published Year	2018
Journal	Scientific reports
Title	Genetic divergence of HIV-1 B subtype in Italy over the years 2003-2016 and impact on CTL escape prevalence.
Author	Alteri C,Fabeni L,Scutari R,Berno G,Di Carlo D,Gori C,Bertoli A,Vergori A,Mastrorosa I,Bellagamba R,Mussini C,Colafigli M,Montella F,Pennica A,Mastroianni CM,Girardi E,Andreoni M,Antinori A,Svicher V,Ceccherini-Silberstein F,Perno CF,Santoro MM
Evidence	Interestingly, CTL escape variants occur at seven of these positions, such as the PR position 71 (escape variant: A71V), and the RT positions 35 (escape variant: V35I), 162 (escape variant: S162ACQR), 177 (escape variant: D177E), 202 (escape variant: I202V), 207 (escape variant: Q207GE) and 211 (escape variant: R211K).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation