HIV Mutation Detail Information

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Mutation Information
Mutation Site S162C
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype B
Immune Escape Y
Country Europe;Italy;Asia; Africa;North America;South America
Literature Information
PubMed PMID 30356083
Disease HIV infection/AIDS
Published Year 2018
Journal Scientific reports
Title Genetic divergence of HIV-1 B subtype in Italy over the years 2003-2016 and impact on CTL escape prevalence.
Author Alteri C,Fabeni L,Scutari R,Berno G,Di Carlo D,Gori C,Bertoli A,Vergori A,Mastrorosa I,Bellagamba R,Mussini C,Colafigli M,Montella F,Pennica A,Mastroianni CM,Girardi E,Andreoni M,Antinori A,Svicher V,Ceccherini-Silberstein F,Perno CF,Santoro MM
Evidence Interestingly, CTL escape variants occur at seven of these positions, such as the PR position 71 (escape variant: A71V), and the RT positions 35 (escape variant: V35I), 162 (escape variant: S162ACQR), 177 (escape variant: D177E), 202 (escape variant: I202V), 207 (escape variant: Q207GE) and 211 (escape variant: R211K).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation