HIV Mutation Detail Information

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Mutation Information
Mutation Site S153F
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Relevant Drug INSTIs
Country Taiwan(China)
Literature Information
PubMed PMID 33364799
Disease HIV infection/AIDS
Published Year 2020
Journal Infection and drug resistance
Title Prevalence of HIV-1 Integrase Strand Transfer Inhibitor Resistance in Treatment-Naïve Voluntary Counselling and Testing Clients by Population Sequencing and Illumina Next-Generation Sequencing in Taiwan.
Author Tsai HC,Chen IT,Tsai KW,Lee SS,Chen YS
Evidence Of the 38 patients diagnosed in 2017 who had both NGS and population sequencing data, none had INSTI resistance-associated mutations by population sequencing;however, NGS detected four more INSTI resistance-associated mutations with low frequencies (G163R 3.25%, S153F 3.21%, S153Y 1.36% and Y143H 2.06%).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation