Mutation Information
Mutation Site
|
S148T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Country
|
Belgium |
Literature Information
PubMed PMID
|
20087936
|
Disease
|
Chronic hepatitis B;
Liver cirrhosis
|
Published Year
|
2010 |
Journal
|
Journal of medical virology |
Title
|
Molecular evolutionary analysis and mutational pattern of full-length genomes of hepatitis B virus isolated from Belgian patients with different clinical manifestations. |
Author
|
Pourkarim MR,Amini-Bavil-Olyaee S,Verbeeck J,Lemey P,Zeller M,Rahman M,Maes P,Nevens F,Van Ranst M |
Evidence
|
Clinically important muta-tions, which were located at the major hydrophilicregion (MHR), were sI110L (8%), sS113T (8%), sT118A(16%), sT125M (20%), sQ129H (8%), sM133I/T (8%),sF134Y/F (8%), sS143T (8%), sG145A (4%), sF183S (4%),sA184V (4%), and sS204R (4%)
|
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|