|
Mutation Information
|
Mutation Site
|
S147S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
INSTIs |
|
Country
|
Finland |
Literature Information
|
PubMed PMID
|
28212411
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2017 |
|
Journal
|
PloS one |
|
Title
|
Lack of impact of pre-existing T97A HIV-1 integrase mutation on integrase strand transfer inhibitor resistance and treatment outcome. |
|
Author
|
Abram ME,Ram RR,Margot NA,Barnes TL,White KL,Callebaut C,Miller MD |
|
Evidence
|
1 patient developed T97T/A at Week 12 and then switched primary INSTI resistance pathways to T66T/A and S147S/G at Week 20 before discontinuing study drug 4 weeks later.
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HIV Mutation Detail Information