|
Mutation Information
|
Mutation Site
|
S147G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
INSTIs |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
33480094
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
HIV medicine |
|
Title
|
Virological response and resistance profile in highly treatment-experienced HIV-1-infected patients switching to dolutegravir plus boosted darunavir in clinical practice. |
|
Author
|
Armenia D,Bouba Y,Gagliardini R,Fabeni L,Borghi V,Berno G,Vergori A,Cicalini S,Mussini C,Antinori A,Ceccherini-Silberstein F,Perno CF,Santoro MM |
|
Evidence
|
Among 13 non-responding patients for whom a genotypic resistance test result at failure was available, only two (15.4%) accumulated further resistance in integrase (Y143C/H/R; S147G and N155H) and protease (V32I, L33F, I54L).
|
|
|
HIV Mutation Detail Information