Mutation Information
Mutation Site
|
S147G |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Genotype/Subtype
|
B |
Relevant Drug
|
elvitegravir (EVG) |
Country
|
Finland |
Literature Information
PubMed PMID
|
28212411
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2017 |
Journal
|
PloS one |
Title
|
Lack of impact of pre-existing T97A HIV-1 integrase mutation on integrase strand transfer inhibitor resistance and treatment outcome. |
Author
|
Abram ME,Ram RR,Margot NA,Barnes TL,White KL,Callebaut C,Miller MD |
Evidence
|
None of these pre-treatment integrase sequences contained primary integrase mutations most often associated with emergent EVG (T66I, E92Q, S147G, Q148R/H/K, and N155H) or RAL (Y143C/R/H, Q148H/K/R, and N155H) resistance.
|
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