|
Mutation Information
|
Mutation Site
|
S147A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Large T |
|
Viral Reference
|
DQ305492.1;
NC_001699.1;
NC_009238.1;
GU296381.1;
JF813003.1;
HM011563.1;
HM011564.1;
NC_014361.1;
NC_015150.1;
JQ898292.1;
NC_020106.1;
NC_020890.1;
NC_024118.1;
NC_034253.1 |
Literature Information
|
PubMed PMID
|
32962090
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Merkel Cell Polyomavirus Large T Antigen Unique Domain Regulates Its Own Protein Stability and Cell Growth. |
|
Author
|
Nwogu N,Ortiz LE,Kwun HJ |
|
Evidence
|
Due to this double phosphorylation requirement, we further examined and replicated the interaction study of S142 and S147 alanine substitution mutants (MCV LT S142A and MCV LT S147A) with beta-TrCP along with a double mutant S142A/S147A (MCV LTS142A/S147A).
|
|
|
MCV Mutation Detail Information