|
Mutation Information
|
Mutation Site
|
S143W |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
16963200
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Gene |
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Title
|
A unique amino acid substitution, T126I, in human genotype C of hepatitis B virus S gene and its possible influence on antigenic structural change. |
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Author
|
Ren F,Tsubota A,Hirokawa T,Kumada H,Yang Z,Tanaka H |
|
Evidence
|
At site 143, in contrast, two amino acid substitutions, T143S and S143W, caused only minor changes in the hydropathy parameter (threonine: − 0.7; serine: − 0.8; tryptophan: − 0.9).
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HBV Mutation Detail Information