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Mutation Information
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Mutation Site
|
S143T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A3;A4 |
|
Relevant Drug
|
lamivudine (LAM);emtricitabine (FTC);efavirenz (EFV);zidovudine (AZT);tenofovir (TDF);Abacavir (ABC);Didanosine (DDI);Lopinavir (LPV);ritonavir |
|
Country
|
Gabon |
Literature Information
|
PubMed PMID
|
29315352
|
|
Disease
|
HBV-HIV coinfection
|
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Published Year
|
2018 |
|
Journal
|
PloS one |
|
Title
|
Hepatitis B infection among HIV infected individuals in Gabon: Occult hepatitis B enhances HBV DNA prevalence. |
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Author
|
Bivigou-Mboumba B,Amougou-Atsama M,Zoa-Assoumou S,M'boyis Kamdem H,Nzengui-Nzengui GF,Ndojyi-Mbiguino A,Njouom R,François-Souquière S |
|
Evidence
|
However, 60% of our strains had the S143T polymorphic mutation followed by G145K and K141R (for 2 patients) and M133I and D144N (for one patient)
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HBV Mutation Detail Information