|
Mutation Information
|
Mutation Site
|
S143L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.P120Q+s.T118R+s.S117N+s.Q101H+s.S143L |
|
Genotype/Subtype
|
D |
|
Viral Reference
|
AY721605
|
|
Country
|
Turkey |
Literature Information
|
PubMed PMID
|
17210268
|
|
Disease
|
HBV infection
|
|
Published Year
|
2007 |
|
Journal
|
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology |
|
Title
|
A new hepatitis B virus vaccine escape mutation in a renal transplant recipient. |
|
Author
|
Sayiner AA,Agca H,Sengonul A,Celik A,Akarsu M |
|
Evidence
|
The sequencing data showed that the HBV strain carried five amino acid substitutions in the major hydrophilic region of the S protein, one (sS143L) located at the "a" determinant. A commercial HBsAg assay failed to detect the mutant antigen.
|
|
|
HBV Mutation Detail Information