|
Mutation Information
|
Mutation Site
|
S143L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
rt.F151F+s.S143L |
|
Amino acid_Mutation
|
C582T |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
16428891
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Intervirology |
|
Title
|
Characterization of naturally occurring and Lamivudine-induced surface gene mutants of hepatitis B virus in patients with chronic hepatitis B in India. |
|
Author
|
Kazim SN,Sarin SK,Sharma BC,Khan LA,Hasnain SE |
|
Evidence
|
Two (3.5%) patients had naturally occurring HBV mutants, sP127S and sS143L seen in the 'a' determinant of the S-gene.
|
|
|
HBV Mutation Detail Information