HBV Mutation Detail Information

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Mutation Information
Mutation Site S142P
Mutation Type Amino acid level
Gene/Protein/Region Type S
Literature Information
PubMed PMID 10596008
Disease HBV infection
Published Year 2000
Journal Journal of medical virology
Title Effect of variation in the common "a" determinant on the antigenicity of hepatitis B surface antigen.
Author Seddigh-Tonekaboni S,Waters JA,Jeffers S,Gehrke R,Ofenloch B,Horsch A,Hess G,Thomas HC,Karayiannis P
Evidence The variant P142S/G145R was also not bound by themonoclonal antibodies or the AUSRIA II assay even ata concentration of 310 ng/ml but the protein containinga change of proline for serine at amino acid 142 alonewas detectable using all of the monoclonal antibodies

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation