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Mutation Information
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Mutation Site
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S142A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Large T |
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Viral Reference
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DQ305492.1;
NC_001699.1;
NC_009238.1;
GU296381.1;
JF813003.1;
HM011563.1;
HM011564.1;
NC_014361.1;
NC_015150.1;
JQ898292.1;
NC_020106.1;
NC_020890.1;
NC_024118.1;
NC_034253.1 |
Literature Information
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PubMed PMID
|
32962090
|
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Published Year
|
2020 |
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Journal
|
Viruses |
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Title
|
Merkel Cell Polyomavirus Large T Antigen Unique Domain Regulates Its Own Protein Stability and Cell Growth. |
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Author
|
Nwogu N,Ortiz LE,Kwun HJ |
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Evidence
|
Due to this double phosphorylation requirement, we further examined and replicated the interaction study of S142 and S147 alanine substitution mutants (MCV LT S142A and MCV LT S147A) with beta-TrCP along with a double mutant S142A/S147A (MCV LTS142A/S147A).
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MCV Mutation Detail Information