Mutation Information
Mutation Site
|
S132P |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
A |
Country
|
South Africa |
Literature Information
PubMed PMID
|
27031988
|
Disease
|
Occult HBV infection;
Chronic hepatitis B
|
Published Year
|
2016 |
Journal
|
The Journal of general virology |
Title
|
Functional analysis of 'a' determinant mutations associated with occult HBV in HIV-positive South Africans. |
Author
|
Powell EA,Boyce CL,Gededzha MP,Selabe SG,Mphahlele MJ,Blackard JT |
Evidence
|
Of the seven mutations analysed, four (S132P, C138Y, N146D and C147Y) resulted in decreased HBsAg expression in one viral background but not in the second viral background.
|
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