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Mutation Information
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Mutation Site
|
S119R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
dolutegravir (DTG);raltegravir (RAL) |
|
Country
|
Germany |
Literature Information
|
PubMed PMID
|
25397494
|
|
Disease
|
HIV-HCV coinfection
|
|
Published Year
|
2014 |
|
Journal
|
Journal of the International AIDS Society |
|
Title
|
New dolutegravir resistance pattern identified in a patient failing antiretroviral therapy. |
|
Author
|
Carganico A,Dupke S,Ehret R,Berg T,Baumgarten A,Obermeier M,Walter H |
|
Evidence
|
In June 2013, after S119R, N155H and E157Q mutations in viral integrase were detected, the patient received DTG, and RAL was stopped.
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HIV Mutation Detail Information