HIV Mutation Detail Information

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Mutation Information

Mutation Site	S115V
Mutation Type	Amino acid level
Gene/Protein/Region Type	Gp120

Literature Information

PubMed PMID	31980614
Published Year	2020
Journal	Nature communications
Title	Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements.
Author	Henderson R,Lu M,Zhou Y,Mu Z,Parks R,Han Q,Hsu AL,Carter E,Blanchard SC,Edwards RJ,Wiehe K,Saunders KO,Borgnia MJ,Bartesaghi A,Mothes W,Haynes BF,Acharya P,Munir Alam S
Evidence	The F15 mutant included the F14 mutations in addition to a gp120 outer-domain mutation N377L with F11 including mutations S115V, H72P, and H66S in addition to the F15 mutations.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation