Mutation Information
Mutation Site
|
R90K |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Vpr |
Literature Information
PubMed PMID
|
32778120
|
Published Year
|
2020 |
Journal
|
Journal of translational medicine |
Title
|
Impact of HIV-1 Vpr manipulation of the DNA repair enzyme UNG2 on B lymphocyte class switch recombination. |
Author
|
Eldin P,Péron S,Galashevskaya A,Denis-Lagache N,Cogné M,Slupphaug G,Briant L |
Evidence
|
It was also detected to the same extent for the Vpr R90K mutant which was unable to induce G2/M cell cycle arrest but still competent to interact with human UNG2 (Fig.
|
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