|
Mutation Information
|
Mutation Site
|
R80A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Vpr |
Literature Information
|
PubMed PMID
|
17140287
|
|
Published Year
|
2006 |
|
Journal
|
PLoS pathogens |
|
Title
|
HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT. |
|
Author
|
Andersen JL,DeHart JL,Zimmerman ES,Ardon O,Kim B,Jacquot G,Benichou S,Planelles V |
|
Evidence
|
As a control, we used isogenic vectors expressing a mutant form of Vpr, pHR-VPR(R80A), wherein Vpr(R80A) is defective in induction of G2 arrest and apoptosis.
|
|
|
HIV Mutation Detail Information