|
Mutation Information
|
Mutation Site
|
R77C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E7 |
|
Amino acid_Mutation
|
C790T |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
Romania |
Literature Information
|
PubMed PMID
|
25143263
|
|
Disease
|
Cervical carcinoma;
Squamous-cell carcinoma;
Cervical intraepithelial neoplasia
|
|
Published Year
|
2014 |
|
Journal
|
Archives of virology |
|
Title
|
Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients. |
|
Author
|
Plesa A,Anton G,Iancu IV,Diaconu CC,Huica I,Stanescu AD,Socolov D,Nistor E,Popa E,Stoian M,Botezatu A |
|
Evidence
|
The most prevalent missense mutations in HPV16 E7 (C749T and C790T) were found in 21 cases, leading to the amino acid changes S63F and R77C, respectively.
|
|
|
HPV Mutation Detail Information