Home
Virus
Gene
Disease
Dataset
Download
Help
 
HIV Mutation Detail Information

> R77A Search Result


Mutation Information
Mutation Site R77A
Mutation Type Amino acid level
Gene/Protein/Region Type Vpr
Literature Information
PubMed PMID 11181702
Published Year 2001
Journal The Journal of experimental medicine
Title Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2.
Author Jacotot E,Ferri KF,El Hamel C,Brenner C,Druillennec S,Hoebeke J,Rustin P,Métivier D,Lenoir C,Geuskens M,Vieira HL,Loeffler M,Belzacq AS,Briand JP,Zamzami N,Edelman L,Xie ZH,Reed JC,Roques BP,Kroemer G
Evidence Vpr52-96 (but not the NH2-terminal moiety of Vpr [Vpr1-51] or mutated Vpr52-96, in which arginine 77 is replaced by alanine, Vpr52-96[R77A]) caused permeabilization of ANT proteoliposomes (Fig.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation