Mutation Information
Mutation Site
|
R71T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Nef |
Literature Information
PubMed PMID
|
25212771
|
Published Year
|
2014 |
Journal
|
Retrovirology |
Title
|
Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection. |
Author
|
Ritchie AJ,Cai F,Smith NM,Chen S,Song H,Brackenridge S,Abdool Karim SS,Korber BT,McMichael AJ,Gao F,Goonetilleke N |
Evidence
|
The R71T change at position 4 in the Nef68-76 epitope, which was first detected at day 134 and was present in 100% of SGA sequences at day 441, abrogated all detectable T cell recognition (Figure 4A).
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