HIV Mutation Detail Information

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Mutation Information

Mutation Site	R683K
Mutation Type	Amino acid level
Gene/Protein/Region Type	Env
Country	America

Literature Information

PubMed PMID	29672607
Disease	HIV infection/AIDS
Published Year	2018
Journal	PLoS pathogens
Title	Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.
Author	Kumar A,Smith CEP,Giorgi EE,Eudailey J,Martinez DR,Yusim K,Douglas AO,Stamper L,McGuire E,LaBranche CC,Montefiori DC,Fouda GG,Gao F,Permar SR
Evidence	To understand the role of amino acids at position 662 and 683 in resistance of infant T/F viruses against maternal plasma, two gp41 mutants R683K and Q662E were generated for 100997i and 102407i T/F env genes respectively.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation