|
Mutation Information
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Mutation Site
|
R62P |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Vpr |
Literature Information
|
PubMed PMID
|
15312229
|
|
Published Year
|
2004 |
|
Journal
|
Retrovirology |
|
Title
|
Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae. |
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Author
|
Yao XJ,Rougeau N,Duisit G,Lemay J,Cohen EA |
|
Evidence
|
In contrast, expression of helices I and III Vpr mutants, E21K, L23F, A30F and R62P, which displayed a strong attenuation of binding to GST-B4, did not lead to HP-16 budding yeast growth arrest.
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HIV Mutation Detail Information