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HIV Mutation Detail Information

> R62D Search Result


Mutation Information
Mutation Site R62D
Mutation Type Amino acid level
Gene/Protein/Region Type Vpr
Combined Mutation vpr.F69A+vpr.R62D
Literature Information
PubMed PMID 33648539
Published Year 2021
Journal Virology journal
Title HIV-1 Vpr activates host CRL4-DCAF1 E3 ligase to degrade histone deacetylase SIRT7.
Author Zhou X,Monnie C,DeLucia M,Ahn J
Evidence To further understand the role of Vpr in mediating SIRT7 down-regulation, we generated a Vpr mutant R62D/F69A.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation