|
Mutation Information
|
Mutation Site
|
R57S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Tat |
|
Genotype/Subtype
|
B;C |
|
Viral Reference
|
HXB2
|
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
33462791
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
Journal of neurovirology |
|
Title
|
HIV-1C and HIV-1B Tat protein polymorphism in Southern Brazil. |
|
Author
|
de Almeida SM,Rotta I,Vidal LRR,Dos Santos JS,Nath A,Johnson K,Letendre S,Ellis RJ,H. I. V. Neurobehavioral Research Center (HNRC) Group. |
|
Evidence
|
The frequency of the R57S substitution among the HIV-1C sequences from Brazil was 74% vs. 20% in HIV-1B (p = 0.004), and that of substitution Q63E in HIV-1C was 80% and 20% in HIV-1B (p < 0.0001).
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HIV Mutation Detail Information